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During a forum held at the Vth ������ϲʿ�������ֳ�ֱ�� World Parks Congress in South Africa in 2003, the Wildlife Conservation Society (WCS) and the ������ϲʿ�������ֳ�ֱ�� SSC Veterinary and Southern Africa Sustainable Use Specialist Groups (VSG and SASUSG) brought together nearly 80 experts from Africa and beyond to develop ways to tackle the immense health-related conservation and development challenges at the wildlife/domestic animal/human interface facing East and Southern Africa today, and tomorrow. This volume focuses on several themes of critical importance to the future of animal agriculture, wildlife, and, of course, people: competition over grazing and water resources, disease mitigation, local and global food security and other potential sources of conflict related to the overall challenges of land-use planning and the pervasive reality of resource constraints. This publication seeks to draw attention to the need to move towards a “one health” perspective – an approach that was the foundation of the discussions in Durban, and a theme pervading these thought-provoking, insightful, and practical Proceedings.